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Karen Rowland Yeo, PhD

Senior Vice President
Certara UK Ltd

In her current strategic role, Dr. Rowland-Yeo aims to broaden application of physiologically-based pharmacokinetic (PBPK) modeling and simulation to enable individualized dosing recommendations for therapeutics as well as garnering acceptance of PBPK modeling in underserved populations and extend the approach to global health scenarios. Prior to her current role, Dr. Rowland-Yeo was the Head of PBPK Consultancy at Certara UK Ltd (Simcyp Division; 2015-2019) where she built and subsequently led a core team of scientists engaged in consultancy projects relating to the application of PBPK modeling in drug development. In this role, she drove development of best practices and worked directly with global regulators to gain acceptance of PBPK models. Prior to joining Simcyp in 2002, she was a lecturer of Clinical Pharmacology & Therapeutics at the University of Sheffield. Dr. Rowland-Yeo holds a PhD degree in Drug Metabolism from the University of Sheffield with a research focus in translational & experimental Clinical Pharmacology, as applied in studies of CYP2D6 and associated drug interactions. Following this, she pursued postdoctoral research as a Leukemia Research Fund Fellow. Throughout her career, Dr. Rowland-Yeo has authored/co-authored more than 100 publications in peer-reviewed journals in the areas of clinical pharmacology, drug metabolism and drug-drug interactions. She serves as the Deputy Editor in Chief of Clinical Pharmacology and Therapeutics: Pharmacometrics and Systems Pharmacology journal and is an active member of the ASCPT Scientific program Committee.

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